pleomorphic adenomas การใช้
- The benign tumors include ceruminous adenoma, ceruminous pleomorphic adenoma, and ceruminous syringocystadenoma papilliferum.
- Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals.
- PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas.
- PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands.
- In approximately 75 % of cases ca ex PAs arise in a pleomorphic adenoma that is apparent when the tumour is excised.
- Tumors arising from other tissues may also produce a cartilage-like matrix, the best known being pleomorphic adenoma of the salivary glands.
- Catenins are known to be associated with colorectal and ovarian cancer, and they have been identified in pilomatrixoma, medulloblastoma, pleomorphic adenomas, and malignant mesothelioma.
- In some cases tumors that formed in other tissues may produce a cartilage-like matrix, an example of this is the pleomorphic adenoma of the sexual reproduction salivary glands.
- "' Pleomorphic adenoma "'is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality.
- Matrix families of interest include the Huntington's disease gene regulatory region, nerve growth factor, nuclear respiratory factor, pleomorphic adenoma gene, zinc finger transcription factors, and an E2F-myc activator / cell cycle regulator.
- In the other approximately 25 % of cases the individual had a pleomorphic adenoma excised previously and the diagnosis is made based on ( 1 ) the presence of a carcinoma, and ( 2 ) the history of a pleomorphic adenoma at that location.
- In the other approximately 25 % of cases the individual had a pleomorphic adenoma excised previously and the diagnosis is made based on ( 1 ) the presence of a carcinoma, and ( 2 ) the history of a pleomorphic adenoma at that location.